Pediatric Antifungal Overview 


This reference library was created for the community of providers who care for children with these illnesses. It was developed to assist clinicians in understanding, diagnosing and treating pediatric invasive fungal infections. The library links to important references within each category but is not meant to be comprehensive. 


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International Pediatric Fungal Network, Box 3499, Duke University Medical Center, Durham, NC 27710. USA.   Tel: 919-668-4847 Email:

Rational approach to pediatric antifungal therapy. 

Steinbach WJ. Adv Exp Med Biol. 2011;697:231-42.

Immunotherapy against invasive mold infections. 

Antachopoulos C et al. Immunotherapy. 2012 Jan;4(1):107-20.

Invasive fungal disease in PICU: Epidemiology and risk factors. 

Brissaud O et al. Ann Intensive Care. 2012 Feb 22;2(1):6.

Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections. 

Blyth CC et al. Cochrane Database Syst Rev. 2010 Feb 17;(2):CD006343.

Pediatric antifungal utilization: New drugs, new trends. 

Prasad PA et al. Pediatr Infect Dis J. 2008 Dec;27(12):1083-8.

Pediatric antifungal agents. 

Cohen-Wolkowiez M et al. Curr Opin Infect Dis. 2009 December; 22(6): 553–558.

Not just little adults: Candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. 

Blyth CC et al. Pediatrics. 2009 May;123(5):1360-8.

Pediatric antifungal drug development: Lessons learned and recommendations for the future.

Watt KM et al. Pediatr Infect Dis J. 2012 Jun;31(6):635-7.

Critical importance of antifungal dosing in children. 

Steinbach WJ. Expert Rev Anti Infect Ther. 2011 Mar;9(3):283-4.

Pediatric invasive fungal infections: realities, challenges, concerns, myths and hopes. 

Dinleyici EC et al. Expert Rev Anti Infect Ther. 2011 Mar;9(3):273-4. 

Update on antifungal resistance in children: epidemiology and recommendations. 

Verweij PE et al. Pediatr Infect Dis J. 2013 May;32(5):556-7.

Antifungal prophylaxis in pediatric hematology/oncology: New choices & new data. 

Dvorak CC et al. Pediatr Blood Cancer. 2012 Jul 15;59(1):21-6.

Antifungal therapy and outcomes in infants with invasive Candida infections. 

Ascher SB et al. Pediatr Infect Dis J. 2012 May;31(5):439-43.

Antifungal agents for the treatment of systemic fungal infections in children. 

Allen U. Can J Infect Dis Med Microbiol. 2010 Winter;21(4):e116-21.